Rhenium Compounds as Anticancer Agents
A novel variation on metal-based anticancer compounds which shows equivalent effect and lower toxic side effects compared with existing approved medications.
Expandable Orthopaedic Screw
An orthopaedic screw with significantly increased fixation strength (up to 90 per cent) compared to equivalent conventional screws without compromising removability.
Atomised Rapid Injection for Solvent Extraction
A fluid anti-solvent extraction technology which generates micron and sub-micron size particles of active pharmaceutical agents (APIs) that are more readily absorbed by the body.
Anti-diabetics which activate endogenous hormone release
A new class of synthetic analogues that have very low toxicity and few side effects that represent a new approach to the management of Type 2 diabetes.
Selectively targeting gamma-secretase
The proposed project will ultimately offer potential targets for designing more selective small molecule therapeutics aimed at treating AD by slowing down or preventing build-up of pathogenic Aβ.
Nanodelivery to the brain
A delivery system which uses nanoparticles combined with dual targeting ligands for delivery of a wide variety of payloads into the brain.